Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by neurofibrillary tangles, amyloid beta aggregation, and neuronal dysfunction and loss. Research into various therapeutic approaches to prevent AD onset is a significant field of study as no definitive cure currently exists. Globally, studies recognize herbal therapies for their accessibility, affordability, and health-promoting properties against neurodegenerative diseases. Matcha tea in particular, from the Camellia sinensis plant, comprises of components such as epigallocatechin-3-gallate (EGCG), caffeine, L-theanine, rutin, and quercetin which possess several anti-AD health-promoting properties. However, further research into the effects of individual components in matcha towards specific diseases is valid and required. Therefore, this study synthesized a comprehensive assessment of the specific AD-associated factors that matcha tea exhibited beneficial effects towards. The research methodology consisted of a secondary review and analysis of peer-reviewed research articles and primary sources. Epidemiological studies were utilized to investigate the various mechanisms that individual components in matcha employed against AD pathology and hallmarks. The research was compiled into a table demonstrating which components in matcha were associated with alleviating certain AD-associated factors. Finally, the practical applications of matcha and future considerations in the field were discussed. The results indicated that matcha’s components beneficially affected numerous AD hallmarks and employed various mechanisms to mitigate AD symptoms. Based on the results, it was concluded that matcha possesses several anti-AD health-promoting properties that may supplement and amplify current prevention strategies. Therefore, this study recommends matcha consumption as a preventative measure against AD.
Parupalli et al. (Sat,) studied this question.
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