Figure S3 from Genome-Wide CRISPR Screening Reveals That mTOR Inhibition Initiates Ferritinophagy and Ferroptosis in Head and Neck Cancer

Key Points

• mTOR inhibition induces ferroptosis in head and neck cancer, enhancing tumor cell death.
• Targeted drug screening revealed significant effects on ferroptosis through mTOR inhibition.
• Observational analysis indicates mTOR inhibitors may serve as effective treatments against head and neck cancer.
• Findings suggest the need for further investigation of mTOR inhibition in clinical settings.

Abstract