Figure S16 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Key Points

• TGFβ inhibition significantly enhances immune cell infiltration and reduces metastases in Ewing sarcoma models.
• Experimental results indicate improved survival rates for mice treated with TGFβ inhibition and radiotherapy.
• The approach involved assessing survival of mice treated with ± RER and ± radiation therapy.
• These findings suggest TGFβ inhibition during radiotherapy may improve outcomes for Ewing sarcoma, highlighting a potential therapeutic strategy.