Figure S7 from TGFβ Inhibition during Radiotherapy Enhances Immune Cell Infiltration and Decreases Metastases in Ewing Sarcoma

Key Points

• Inhibition of TGFβ during radiotherapy decreases metastases in ewing sarcoma, improving patient outcomes.
• Bulk RNA sequencing indicated enhanced immune cell infiltration in tumors treated with TGFβ inhibition.
• Observational analysis of ewing sarcoma tumors in hu-CD34+ and NSG mouse models revealed significant interactions.
• These findings support further research on TGFβ as a therapeutic target in ewing sarcoma treatment.