Total Synthesis of (±)-Lycojapomines A and B

Key Points

• Total synthesis achieved for both lycojapomines A and B, showcasing effective use of innovative chemical reactions.
• Key techniques included photoinduced radical cyclization and ozonolysis, crucial for the successful synthesis.
• Approach involved specific cyclization methods, specifically 5-endo-dig cyclization and aza-silyl-Prins reaction, to form desired compounds.
• Significance lies in advancing synthesis methods for lycopodium alkaloids, highlighting potential for drug development.