Cobalt-Catalyzed Direct Carbonylative 3-Acylation of (N-H)Indoles with Alkyl Halides

Key Points

• This method allows effective carbonylative acylation of indoles, expanding synthetic utility.
• The transformation enhances C-H functionalization using cobalt catalysts with high selectivity.
• Intermolecular reactions were successfully achieved using various alkyl halides in the procedure.
• Overall, this approach provides a novel strategy for utilizing heterocycles in organic synthesis.