This review summarizes current evidence on the use of polymer post-and-core inlays fabricated by 3D printing for the restoration of endodontically treated teeth. Based on a search of publications from 2021–2025 in PubMed, ScienceDirect, MDPI, Google Scholar, and eLibrary, more than 50 papers were screened; according to relevance, full-text availability, and clinical focus, 14 articles—including clinical observations, in-vitro experiments, and systematic reviews—were selected for analysis. The studies show that 3D-printed polymer constructs are bioinert, non-corroding, and have an elastic modulus close to dentin, thereby reducing the risk of root fractures typical of metal and zirconia systems. The high accuracy of digital design ensures a snug fit and allows the extent of tooth preparation to be reduced, preserving up to one quarter of hard dental tissues, while optimized post-processing (UV curing in a nitrogen atmosphere and polishing) decreases surface roughness and improves bonding. These advantages, together with a 40–60% reduction in laboratory time and an approximately one-third reduction in treatment costs, support the cost-effectiveness of the technology. Clinical case series with five-year follow-up demonstrate stable restorations with no signs of failure and preserved function. Limitations include the need for expensive equipment, high energy consumption, and a shortage of clinical trial data. Overall, the findings indicate that polymer 3D inlays are a promising alternative to traditional systems; however, their reliability should be definitively confirmed by larger clinical studies with follow-up periods exceeding five years.
Minasyan et al. (Mon,) studied this question.