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October 12, 2025Open Access

A Brief Study on Papaya (Carica Papaya) – A Review

GSGayatri Ashok Shirsat MJMohini Raju Jejurkar PBPrasad Sopan Bhongal

Key Points

Carica papaya shows significant antibacterial and anti-inflammatory effects on acne vulgaris, highlighting its potential as a natural treatment.
The presence of bioactive compounds like papain and flavonoids provides papaya with keratolytic and antioxidant properties, enhancing treatment efficacy.
Herbal-based formulations utilizing carica papaya offer a safer alternative to synthetic treatments often linked to irritation and resistance.
The review focuses on pharmacognosy and phytochemistry associated with papaya, supporting its incorporation in polyherbal anti-acne cream.

Abstract

Acne vulgaris is a multifactorial inflammatory disorder of the pilosebaceous unit, primarily affecting adolescents and young adults. Synthetic anti-acne treatments, though effective, often cause irritation and antibiotic resistance. Consequently, herbal-based formulations are gaining popularity due to their safety and efficacy. Carica papaya (papaya) is a tropical fruit-bearing plant known for its remarkable dermatological and pharmacological properties. Its bioactive compounds—papain, chymopapain, flavonoids, alkaloids, and vitamins—exhibit antibacterial, antioxidant, keratolytic, and anti-inflammatory actions. This review emphasizes the pharmacognosy, phytochemistry, pharmacological activities, and potential of papaya in polyherbal anti-acne cream formulations

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