October 17, 2025Open Access

Supplementary Figure 4 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

Key Points

Genomic alterations in patients were identified using plasma and tumor tissue samples, which adds to the understanding of mutation detection.
Patients receiving taselisib with PIK3CA mutations showed varying treatment responses, depicted by response stratification.
The analysis involved comparing the presence of mutations in both tissue and plasma, offering insights into the mutations’ distribution.
Findings highlight the importance of accurate mutation detection in guiding treatment decisions for patients involved in the trial.

Abstract

Supplementary Figure 4. Genomic alterations detected in patients treated in subprotocol I enrolling patients with PIK3CA mutations who received treatment with taselisib. Patients are stratified according to the best overall response. Triangles are used to depict the presence of mutation in tissue (lower triangle) and/or plasma (upper triangle).

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Authors

Mohamed A. Gouda

Filip Janků

Ying Yuan

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Supplementary Figure 4 from Concordance between Tumor Tissue and Plasma DNA Genotyping in the NCI-MATCH Trial (EAY131)

Key Points

Abstract

Citation Network

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Discussion

Authors

Actions

References and Citations

Citation Network

Connected Papers

Discussion

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