Can percutaneous Melody valve placement successfully treat severe neoaortic valve stenosis in an adult with hypoplastic left heart syndrome and Fontan circulation?
31-year-old patient with hypoplastic left heart syndrome and Fontan circulation, presenting with severe neoaortic valve stenosis and moderate regurgitation (n=1)
Percutaneous Melody valve placement in the neoaortic position
Successful treatment of neoaortic valve stenosis and regurgitation
Percutaneous Melody valve placement can be a successful treatment option for severe neoaortic valve stenosis in adult patients with hypoplastic left heart syndrome and Fontan circulation.
The Melody valve (Medtronic) is commonly used for pulmonary valve replacement in patients with dysfunctional right ventricle to pulmonary artery conduits or bioprosthetic pulmonary valves. Rare reports exist of its use in the aortic position, including only 1 prior description of its use in a patient with hypoplastic left heart syndrome. We describe a 31-year-old patient with hypoplastic left heart syndrome who had severe neoaortic valve stenosis and moderate regurgitation that was successfully treated with percutaneous Melody valve placement in the neoaortic position.
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Matthew Schwartz
Adult Congenital Heart Association
Jorge R. Alegría
Atrium Medical Cente
Jonathan Schwartz
Mayo Clinic
Journal of the Society for Cardiovascular Angiography & Interventions
Atrium Medical Cente
Levine Children's Hospital
Adult Congenital Heart Association
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Schwartz et al. (Tue,) studied this question.
synapsesocial.com/papers/6a0fdc8f8090e499da6042b4 — DOI: https://doi.org/10.1016/j.jscai.2025.104018