The TAPSE/sPAP ratio moderately correlates with the CMR-derived SV/ESV ratio (r=0.49, p=0.004), supporting its use to assess ventriculoarterial coupling in PAH.
Does the echocardiographic TAPSE/sPAP ratio correlate with the CMR-derived SV/ESV ratio in patients with pulmonary arterial hypertension?
The echocardiographic TAPSE/sPAP ratio moderately correlates with the CMR-derived SV/ESV ratio, supporting its use as a noninvasive parameter for evaluating right ventriculoarterial coupling in PAH.
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Abstract Introduction Right ventriculoarterial uncoupling has been associated with poor outcomes in pulmonary arterial hypertension (PAH) patients, as assessed noninvasively using the tricuspid annular plane systolic excursion/systolic pulmonary artery pressure (TAPSE/sPAP) ratio through two-dimensional (2D) echocardiography and the stroke volume/end-systolic volume (SV/ESV) ratio derived from cardiac magnetic resonance (CMR). Due to several limitations in both TAPSE and sPAP measurements, the use of the TAPSE/sPAP ratio in the assessment of ventriculoarterial coupling is being questioned. However, the SV/ESV ratio obtained through CMR correlates better with invasively measured end-systolic/arterial elastance. Purpose We aimed to evaluate whether there is a correlation between these noninvasive measures of ventriculoarterial coupling. Methods Thirty-four patients with idiopathic PAH (IPAH), connective tissue disease (CTD)-associated PAH, congenital heart disease (CHD)-associated PAH, and portal hypertension-associated PAH were included in this study. Patients with other types of pulmonary hypertension were excluded. 2D echocardiographic evaluation and CMR imaging were performed on the same day. The correlation between the TAPSE/sPAP ratio and the SV/ESV ratio were evaluated. Results We included 17 (50%) patients with IPAH, 13 (38.2%) patients with CTD-associated PAH, 3 (8.8%) patients with CHD-associated PAH, and 1 (2.9%) patient with portal hypertension-associated PAH. The mean age of all patients was 62 ± 14.4 years and 76.5% were female (Table 1). The mean TAPSE/sPAP ratio was 0.36 ± 0.17 mm/mmHg and CMR SV/ESV ratio was 1.08 ± 0.38. The TAPSE/sPAP ratio was moderately correlated with CMR derived SV/ESV ratio (r=0.49, p=0.004) (Figure 1). Conclusions The TAPSE/sPAP ratio correlates with the SV/ESV ratio derived from CMR and serves as a reliable and easily assessable parameter for evaluating ventriculoarterial coupling.
Colak et al. (Sat,) reported a other. The TAPSE/sPAP ratio moderately correlates with the CMR-derived SV/ESV ratio (r=0.49, p=0.004), supporting its use to assess ventriculoarterial coupling in PAH.
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