Ischemic and Bleeding Events After Early Initiation of Direct Oral Anticoagulants for Acute Intracranial Hemorrhage With Non-Valvular Atrial Fibrillation　― A Multicenter Prospective Registry ―

Key Points

• This research assesses the risks of ischemic and hemorrhagic events following the early initiation of direct oral anticoagulants in patients with atrial fibrillation after intracranial hemorrhage.
• Multicenter prospective registry study
• Evaluation of ischemic and hemorrhagic events
• Focus on patients with non-valvular atrial fibrillation post-intracranial hemorrhage
• Increased ischemic risks noted post-early DOAC initiation
• Bleeding events also elevated after ICH
• Efficacy and safety of early DOAC use remain uncertain for this population