• Dipotassium oxalate mouthrinses reduced dentin surface loss compared with the control. • Oxalate–fluoride–stannous mouthrinse showed one of the lowest dentin surface loss values. • Calcium oxalate deposition may have contributed to dentin surface protection. • Dentin showed greater response to oxalate-based anti-erosive strategies than enamel. • Oxalate did not enhance enamel protection under the tested conditions. to formulate experimental solutions, simulating mouthrinses, containing 1.4% dipotassium oxalate (OXP) alone, with 225 ppm F⁻ (from NaF), or with 225 ppm F⁻ and 800 ppm Sn²⁺ (from SnCl₂), and to assess their anti-erosive effect on enamel and dentin. bovine enamel and dentin specimens were randomly distributed into 6 groups (n=10/substrate): 1. Distilled water (DIW); 2. F; 3. F+Sn; 4. OXP; 5. OXP+F; 6. OXP+F+Sn. The specimens were submitted to a 5-day erosive-abrasive cycling with 1% citric acid (2 min, pH ∼ 2,4), followed by 60 minutes artificial saliva (4x/day), brushing with a standard fluoride toothpaste (2x/day) and 1 minute immersion in test solutions after each brushing episode. Surface loss (SL, in µm) was measured with an optical profilometer. Additional analyses included the determination of potentially available fluoride in the solutions and scanning electron microscopy of the specimen surfaces. Data were statistically analyzed (α=0.05). OXP+F+Sn showed the lowest SL in enamel and dentin (3.10 ± 1.12 and 3.27 ± 1.27, respectively), differing from F+Sn in dentin (6.24 ± 0.53; p<0.05). In enamel, F+Sn and OXP+F+Sn significantly reduced SL compared with DIW (10.31 ± 0.99; p<0.05). OXP only showed lower SL for dentin compared with DIW (3.71 ± 1.16; p<0.05). Fluoride availability matched the added concentration, with slight reduction in OXP groups. Calcium oxalate crystals were observed in OXP groups micrographs. OXP reduced enamel and dentin surface loss, with a more pronounced effect in dentin, suggesting its potential as protective agent against erosive tooth wear.
SCONTRE et al. (Sun,) studied this question.