Anaphylaxis under Anesthesia in Pediatrics is a rare (1:10,000)1 but a life-threatening event. The common triggers are anesthetic drugs such as neuromuscular blocking agents , antibiotics, propofol and latex. Signs and symptoms of anaphylaxis under anesthesia differ. The most reliable signs under anesthesia are hypotension and bronchospasm in contrast to routine presentations such as rashes, Airway oedema and tachycardia. Treatment requires immediate discontinuation of the suspected agent, administration of IV epinephrine, airway support with oxygen, intravenous fluid resuscitation, and other medications such as H1 and H2 blockers, corticosteroids.
Khalifa et al. (Sun,) studied this question.
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