Adverse outcomes in children with enterovirus meningitis were associated with absence of fever (OR 4.65), seizures (OR 7.40), and comorbidities (OR 5.27).
What are the risk factors for adverse long-term outcomes in children with enterovirus meningitis?
In children with enterovirus meningitis, absence of fever, seizures, and baseline comorbidities are risk factors for adverse outcomes, though the vast majority of infants under 3 months achieve full recovery.
Absolute Event Rate: 0% vs 0%
Abstract Non-polio enteroviruses (EV) are the most common cause of meningitis in children. We conducted a retrospective case series of long-term outcomes in 243 children between 1/1/2013 and 31/12/2023 across four tertiary centres in London. Adverse outcomes were associated with absence of fever at presentation (odds ratio, OR 4.65, 95% CI 1.03, 20.83), presence of seizures (OR 7.40, 95% CI 1.05, 51.96) and presence of comorbidities at baseline (OR 5.27, 95% CI 1.18, 23.47). Full recovery was seen in 153/160 (95.6%) of children who were under 3 months of age. These data may help clinicians to counsel parents and policymakers on streamlining care pathways following hospital discharge.
Broad et al. (Thu,) reported a other. Adverse outcomes in children with enterovirus meningitis were associated with absence of fever (OR 4.65), seizures (OR 7.40), and comorbidities (OR 5.27).