What question did this study set out to answer?

This research aims to understand how peripherally fenestrated contact lenses affect central corneal edema.

March 21, 2026

The Effect of Peripherally Fenestrated Contact Lenses on Corneal Edema‗

Key Points

This research aims to understand how peripherally fenestrated contact lenses affect central corneal edema.
6 subjects (12 eyes) wore steeply fitted contact lenses with varying peripheral fenestrations
Each lens had 0.1-mm diameter peripheral fenestrations
The lenses were worn for 3 hours during each session
Increased fenestrations led to reduced corneal thickening and steepening
Central clouding of the cornea decreased as the number of fenestrations increased
A minimum of 20 fenestrations was necessary for clinically acceptable edema reduction

Abstract

ABSTRACT To determine the effect of peripherally fenestrated contact lenses on central corneal edema, 6 subjects (12 eyes) wore steeply fitted lenses of identical dimensions but with various numbers ofO.l‐mm diameter peripheral fenestrations for 3‐hr periods. At the end of the wearing periods, thickening, steepening, and central clouding of the cornea were generally reduced as the number of fenestrations was increased. However, 20 fenestrations were required before the edema was reduced to a clinically acceptable level.

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