What question did this study set out to answer?

The research aims to identify conditions leading to discoloration in hydrogel contact lenses.

March 21, 2026

Discoloration of Hydrogel Contact Lenses under Standard Care Regimens

Key Points

The research aims to identify conditions leading to discoloration in hydrogel contact lenses.
Examined four types of hydrogel contact lenses over six months
Utilized both in vivo and in vitro standard care regimens
Applied various disinfectants and saline solutions for lens care
Bufilcon A lenses showed significant discoloration due to heat and Lensept disinfection
Discoloration occurred with rinsing and soaking in sorbate-preserved saline
In vitro tests supported the discoloration findings under specific conditions

Abstract

ABSTRACT Four types of hydrogel contact lenses (N = 164) were subjected to in vivo and in vitro standard care regimens for a period of six months. Lens care variables included: (1) heat disinfection in Bausch and Lomb Sensitive Eyes saline solution; (2) heat disinfection in Cooper Unisol 4 sterile, nonpreserved saline solution; (3) American Optical/Reichert Lensept disinfection and storage in Sensitive Eyes saline; and (4) Lensept disinfection and storage in Unisol 4 saline. The study was conducted to determine the conditions under which lens discoloration occurs. The 45% Bufilcon A (55% water) lens showed significant discoloration in vivo with both heat and Lensept disinfection when rinsed and soaked in sorbate‐preserved saline, and in vitro when heat disinfected in sorbate‐preserved saline.

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Cite This Study

Wardlaw et al. (Sun,) studied this question.

synapsesocial.com/papers/69be38356e48c4981c67869d https://doi.org/https://doi.org/10.1002/j.2330-9512.1986.tb01132.x

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