ABSTRACT Four types of hydrogel contact lenses (N = 164) were subjected to in vivo and in vitro standard care regimens for a period of six months. Lens care variables included: (1) heat disinfection in Bausch and Lomb Sensitive Eyes saline solution; (2) heat disinfection in Cooper Unisol 4 sterile, nonpreserved saline solution; (3) American Optical/Reichert Lensept disinfection and storage in Sensitive Eyes saline; and (4) Lensept disinfection and storage in Unisol 4 saline. The study was conducted to determine the conditions under which lens discoloration occurs. The 45% Bufilcon A (55% water) lens showed significant discoloration in vivo with both heat and Lensept disinfection when rinsed and soaked in sorbate‐preserved saline, and in vitro when heat disinfected in sorbate‐preserved saline.
Wardlaw et al. (Sun,) studied this question.