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The study investigates how extreme ambient temperatures affect acute kidney injury hospitalizations, with a focus on demographic differences.

March 27, 2026Open Access

Wcn26-176 Association Between Ambient Temperature Extremes and Acute Kidney Injury Hospitalizations in Japan: A Nationwide Time-Stratified Case-Crossover Study, 2011–2019

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Key Points

The study investigates how extreme ambient temperatures affect acute kidney injury hospitalizations, with a focus on demographic differences.
Analyzed nationwide data of AKI hospitalizations from 2011 to 2019
Used a case-crossover design to compare hospitalization rates during temperature extremes to baseline temperatures
Examined differences based on age and sex
Increased hospitalizations for AKI were linked to extreme heat and cold temperatures
Demographic factors, such as age and sex, influenced the susceptibility to temperature-related AKI
Findings highlight the risk of AKI during temperature extremes, indicating a public health concern

Abstract

Acute kidney injury (AKI) is a severe condition characterized by a sudden decline in kidney function, with high mortality and healthcare costs. Although extreme ambient temperatures, particularly heatwaves, have been linked to increased AKI risk, the effects of both heat and cold exposure across different demographic groups remain unclear. This study examines the association between ambient temperatures and AKI emergency hospitalizations, with a focus on age and sex differences.

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Cite this study

kyzy et al. (Wed,) studied this question.

synapsesocial.com/papers/69c61ff615a0a509bde18673 — DOI: https://doi.org/10.1016/j.ekir.2026.105652

Authors

Aiperi Asanbek kyzy

Hisaaki Nishimura

Nobutoshi Nawa

Tokyo Medical and Dental University

Journals

Kidney International Reports

Actions

Institutions

Tokyo Metropolitan Institute of Public Health

Institute of Science Tokyo

Osh State University

References and Citations

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Wcn26-176 Association Between Ambient Temperature Extremes and Acute Kidney Injury Hospitalizations in Japan: A Nationwide Time-Stratified Case-Crossover Study, 2011–2019

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion