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When ink triggers inflammation: A case of tattoo granuloma confined to red pigment | Synapse

April 11, 2026Open Access

When ink triggers inflammation: A case of tattoo granuloma confined to red pigment

Key Points

To investigate inflammatory reactions caused by red tattoo pigments, specifically focusing on granulomas.
Case report on a patient with a localized granulomatous reaction to tattoo ink.
Observation of inflammatory response to only the red pigment in the tattoo.
Discussion of the implications of using Nd:YAG laser therapy for treatment.
Documentation of a granulomatous reaction exclusively associated with red tattoo ink.
Emphasis on the antigenic potential of red pigment in triggering inflammation.
Considerations on the safety and efficacy of Q-switched Nd:YAG laser therapy in such cases.

Abstract

Tattoo granulomas are chronic inflammatory reactions to exogenous pigments, most frequently involving red ink due to its higher antigenic potential. 1,2We report a localised granulomatous reaction confined exclusively to red pigment and discuss the cautious use of Q-switched neodymium-doped yttrium aluminum garnet (Nd:YAG) laser therapy.

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Cite This Study

Mani et al. (Thu,) studied this question.

synapsesocial.com/papers/69d9e58f78050d08c1b75d54 https://doi.org/https://doi.org/10.25259/jcas_22_2026