Prophylactic Antibiotic Use and Clinical Outcomes in Patients With Child–Pugh A Cirrhosis and Acute Variceal Bleeding: A Retrospective Cohort Study

Key Points

• To examine the effect of prophylactic antibiotic use on clinical outcomes in patients with Child-Pugh A cirrhosis experiencing acute variceal bleeding.
• Retrospective cohort study design
• Assessment of clinical outcomes including treatment failure and mortality
• Evaluation of patients with Child-Pugh A cirrhosis and acute variceal bleeding
• Prophylactic antibiotic use showed no association with 5-day treatment failure
• No significant difference in 6-week mortality rates between antibiotic users and non-users