What does this research mean for the field?

Skin cancers arising from burn scars, particularly squamous cell carcinoma, exhibit aggressive clinical behavior characterized by reduced latency periods and high metastatic potential, necessitating vigilant long-term surveillance and radical initial treatment. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To summarize the clinical behavior, prognosis, and management practices for skin cancer arising from burn scars.

April 25, 2026Open Access

Characteristics and prognosis of skin cancer arising from burn scars: a systematic review

Key Points

To summarize the clinical behavior, prognosis, and management practices for skin cancer arising from burn scars.
Conducted a systematic review of existing literature on burn scar-related skin cancers.
Analyzed epidemiological data and clinical outcomes, focusing on squamous cell carcinoma.
Evaluated the need for international registries and standardized treatment protocols.
Skin cancers from burn scars, particularly SCC, demonstrate aggressive behavior and high metastatic potential.
Reduced latency periods indicate an urgent need for vigilant long-term monitoring.
Calls for enhanced molecular diagnostics and standardized management protocols were strongly supported.

Abstract

Skin cancers arising from burn scars, especially SCC, demonstrate aggressive clinical behavior with significant morbidity and mortality. Reduced latency periods and high metastatic potential highlight the importance of vigilant, long-term surveillance and radical initial treatment. This review provides a contemporary benchmark for epidemiological understanding and supports calls for international registries, molecular diagnostics, and standardized management protocols for burn scar malignancies.

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Discussion

Authors

Abdulmajeed Alhadlaq

Ibraheem M. Kereet

Basma Kamel

Journals

Journal of Plastic Surgery and Hand Surgery

Actions

Institutions

Cairo University

Mansoura University

Al-Azhar University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Characteristics and prognosis of skin cancer arising from burn scars: a systematic review

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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