What question did this study set out to answer?

This research aims to compare the effectiveness of filtered-phase imaging and susceptibility-weighted imaging for detecting paramagnetic rim lesions in multiple sclerosis.

April 28, 2026

Filtered-phase imaging versus susceptibility-weighted imaging for paramagnetic rim lesion detection in multiple sclerosis: A head-to-head comparison

Key Points

This research aims to compare the effectiveness of filtered-phase imaging and susceptibility-weighted imaging for detecting paramagnetic rim lesions in multiple sclerosis.
Conducted a head-to-head comparison of filtered-phase imaging and SWI for PRL detection
Assessed inter-rater agreement between evaluators using both imaging techniques
Filtered-phase imaging demonstrated a higher positive predictive value for detecting PRLs
SWI revealed superior sensitivity and inter-rater reliability for PRL assessment

Abstract

Both techniques reliably detect PRLs with substantial inter-rater agreement. Filtered-phase imaging offers superior positive predictive value, while SWI provides better sensitivity and inter-rater reliability. Further development of a standardized training program for assessment of PRL and studies directly comparing susceptibility-sensitive sequences on different vendor platforms are warranted.

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Cite This Study

Hollen et al. (Sun,) studied this question.

synapsesocial.com/papers/69f04eb8727298f751e729dc https://doi.org/https://doi.org/10.1177/13524585261439651

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