Supplementary document to the DQIS framework (Zenodo DOI: 10. 5281/zenodo. 19855263). Register of scientific objections identified during preparation for academic validation of the DQIS framework — Distributed Quantum-Inspired Immune Surveillance. Version 4. 0 — 12 objections addressed: O1 — Empirical grounding of parameter pᵢ O2 — Statistical independence of channels (balanced group quorum) O3 — Selective pressure at population scale O4 — Channel T-ε: reachability of pᵢ = 0. 01 O5 — DQIS-J: number of paediatric procedures O6 — T-γ* temporal criterion vs T-cell contact time (NFAT-like integration) O7 — Clonal hematopoietic drift (CHIP) disrupts the 5-pool balance of DQIS-A NEW O8 — Progressive epigenetic silencing of transgenes in differentiated T cells NEW O9 — Balanced-quorum co-presence probability in the TME not quantified NEW O10 — Bulk-derived correlations ρᵢj underestimate single-cell correlations NEW O11 — Ci-VSP (Ciona intestinalis) may elicit CTL response against T-γ* cells NEW O12 — Sub-threshold dormant cells (CDIC) systematically evade detection NEW Not a peer-reviewed publication. Prior art deposit. Contact: dqis. research@proton. meRelated documents: - DQIS Consolidated Framework (main document): https: //zenodo. org/records/19877553 - Addendum I — Temporal Stratification of Tail Dependence Risk: https: //zenodo. org/records/19877810
DQIS Research Group (Wed,) studied this question.