Lower respiratory tract infections (LRTIs) remain a significant global health concern with high mortality and morbidity rates. The increasing prevalence of multidrug-resistant (MDR) bacterial pathogens complicates the outcome of treatment. This review aims to highlight the bacterial spectrum linked with LRTIs and antibiotic susceptibility profiles through the synthesis of information in multiple studies conducted in tertiary care settings. The article examines epidemiological patterns, resistance mechanisms, and the implications of epidemiological patterns of clinical investigations conducted over the last decade through a narrative review. Moreover, it investigates how hospital infection control policies, factors affecting host immunity, and approaches to management affect the distribution of bacterial spectra and antibiotic patterns of sensitivity.
Shaik et al. (Wed,) studied this question.