How I do it: intracranially extended C2 schwannoma resection with tailored craniectomy

Abstract Background C2 schwannomas are rare neoplasms presenting with variable extensions. Their possible intracranial involvement and close relationship with the V3 segment of the vertebral artery (VA) require a personalized and delicate surgical approach. Method We describe the resection steps of an extradural C2 schwannoma with intracranial extension. Indications, advantages, and approach-specific complications are discussed. The main surgical steps are illustrated in an operative video. Conclusion A tailored craniectomy adapted to the lesion intracranial extension enables a safe and effective resection of selected extradural, multicompartmental, cranially extended C2 schwannomas.