Preparation and Evaluation of Polyherbal Lozenges for the Treatment of Cough

Herbal lozenges are solid dosage forms meant to dissolve gradually in the mouth, providing localized therapeutic effects in the oral cavity and throat. This review highlights the formulation and creation of herbal lozenges that incorporate natural ingredients like liquorice (Glycyrrhiza glabra), ginger (Zingiber officinale), peppermint (Mentha piperita), and tulsi (Ocimum sanctum), all of which are recognized for their anti-inflammatory, antimicrobial, expectorant, and soothing properties. Lozenges present multiple benefits, including ease of use, extended contact of the medication with throat tissues, enhanced patient adherence, and the capacity to mask unpleasant tastes of the drugs. The study also examines the categorization of lozenges, their benefits and drawbacks, and the function of various excipients such as sucrose, liquid glucose, acacia gum, and citric acid in the formulation process. Herbal extracts were prepared using the maceration method to obtain active phytoconstituents, which were then incorporated into a sugar- based lozenge formulation through extraction techniques. The prepared herbal lozenges provide a natural and effective approach for relieving cough, sore throat, and mild respiratory discomfort while minimizing the side effects associated with synthetic medications. Thus, herbal lozenges represent a promising alternative dosage form for them management of throat and respiratory conditions.