A case of pancreatic neuroendocrine tumor exhibiting spontaneous cystic regression and subsequent regrowth

Key Points

• To report a rare case of spontaneous cystic regression of a pancreatic neuroendocrine tumor followed by regrowth.
• Case report of a 51-year-old female with a history of pancreatic tumor and its regression over time.
• Diagnostic laparoscopic surgery was performed, followed by pathological examination of the resected tumor.
• The initial tumor shrank significantly and almost completely regressed 10 months later.
• Regrowth of the tumor was observed at 27 months, with further increase at 55 months.
• Pathological examination confirmed the diagnosis of pancreatic neuroendocrine tumor (PNEN) G1.