In 2018, type 1 diabetes prevalence in U.S. young adults was 4.2 to 4.7 per 1000, and type 2 diabetes prevalence was 9.1 to 22.3 per 1000, with T2D most prevalent among NH-Black and Hispanic adults.
Cross-Sectional (n=30,000,000)
Yes
This large EHR-based study provides updated prevalence estimates of type 1 and type 2 diabetes among young adults in the U.S., highlighting significant demographic differences.
Introduction and Objective: Diabetes prevalence among young adults in the U.S. is poorly characterized by subtype and within subgroups. We used electronic health records (EHR) to estimate diabetes prevalence by type in 2018 and 2022 among young adults in the U.S. Methods: We used data from five Diabetes in Children, Adolescents, and Young Adults Network centers: four health system centers (HS) (Table 1) and a geographic-based center in Colorado (CO), with a total of more than 30 million young adults under surveillance. We used validated computable phenotypes (CP) to identify adults ages 18 to 45 years with diabetes (type 1 T1D, type 2 T2D). Prevalent cases met the CP within the index year or up to several years prior, depending on center capacity. Results: T1D prevalence in young adults in 2018 was 4.7 (4.6, 4.8) per 1000 among the HS and 4.2 (4.1, 4.3) in CO. T2D prevalence in 2018 was 22.3 (22.2, 22.5) per 1000 for the HS and 9.1 (8.8, 9.3) in CO. T1D was most prevalent among non-Hispanic (NH) White and T2D was most prevalent among NH-Black and Hispanic young adults (Table 1). In most centers, T1D was more prevalent in males versus females and decreased with age; T2D was more prevalent in females and increased with age. Conclusion: This was one of the largest EHR-based studies of diabetes prevalence in young adults in the U.S., providing sufficient sample sizes to generate estimates by subtype and subgroup. Disclosure A.G. Hirsch: None. M. Rosenman: None. J. Divers: None. R. Anthopolos: None. T. Crume: None. D. Dabelea: None. S. Kim: None. A. Rajan: None. N. Laiteerapong: Research Support; Current; Novo Nordisk. B.E. Dixon: None. K. Reynolds: Research Support; Ended; Merck Current; Merck U18DP006512 to University of Florida; U18DP006509 to Geisinger; U18DP006500 to Indiana University and Purdue University at Indianapolis; U18DP006513 to University of South Carolina; U18DP006506 to Kaiser Foundation Hospitals; U18DP006693 and U18DP006694 to Lurie Children’s Hospital; U18DP006517 to University of Colorado Component-A; U18DP006518 to University of Colorado Component-B; and U18DP006633 to New York University Long Island School of Medicine).
Hirsch et al. (Fri,) conducted a cross-sectional in Diabetes (Type 1 and Type 2) (n=30,000,000). Young adults was evaluated on Diabetes prevalence by type (T1D and T2D) per 1000. In 2018, type 1 diabetes prevalence in U.S. young adults was 4.2 to 4.7 per 1000, and type 2 diabetes prevalence was 9.1 to 22.3 per 1000, with T2D most prevalent among NH-Black and Hispanic adults.