Introduction and Objective: Incidence of diabetes in youth is expected to increase in the US and surveillance efforts have faced challenges. Using comprehensive electronic health record data from Kaiser Permanente Southern California (KPSC), we estimated diabetes incidence in youth 0-17 years from 2018-2024. Methods: Denominators included membership counts of youth 18 years on December 31 of the incidence year with ≥ 6 months of continuous membership (except those 1 year of age) and had no prior diagnosis codes, labs, or medications indicative of diabetes dating back to January 1, 2016. Individuals were identified as incident cases if they had a first ICD-10 diabetes diagnosis code in the incident year. Rates were calculated per 100,000 persons. Results: Between 2018 and 2024, the incidence rate of type 1 diabetes (T1D) increased from 11 to 14 and 24 to 25 for youth 0-4 and 5-9 years of age, respectively. (Figure) Incidence of T1D decreased during the same period from 27 to 26 and 28 to 23 for youth 10-14 and 15-17 years of age, respectively. Between 2018 and 2024, incidence of type 2 diabetes (T2D) remained at 23 for youth 10-14 years of age while increasing from 36 to 53 for youth 15-17 years of age; large spikes in incidence were observed in 2021 for T2D. Conclusion: We observed the increases in T1D incidence in youth 10 years and T2D incidence in youth 15-17 years of age, consistent with prior evidence of increasing diabetes incidence among youth. Disclosure M. Mefford: Research Support; Current; Merck Ended; Merck & Co., Inc.
Mefford et al. (Fri,) studied this question.