Native Hawaiian/Pacific Islander and Filipino adolescents and young adults had the highest T2D prevalence (13.2 and 12.5 per 1000), exceeding rates in Black, Hispanic, and Native American groups.
Cohort (n=5,140)
Type 2 diabetes prevalence among Native Hawaiian, Pacific Islander, and Filipino adolescents and young adults is markedly high, exceeding rates in traditionally high-risk groups like Black and Hispanic youth.
Introduction and Objective: Rates of type 2 diabetes (T2D) among adolescents and young adults (AYA; 10-30 years) are rising, yet risk among disaggregated Asian American (AsA), Native Hawaiian and Pacific Islander (NHPI) groups is poorly described. We estimated standardized AYA T2D prevalence within a large integrated health system. Methods: Retrospective cohort study (PAPAYA), using data from Kaiser Permanente Northern California electronic health records. T2D was identified using validated algorithms. The 2024 T2D prevalence was calculated by racial and ethnic group and age- and sex-standardized to the 2020 US census population. Results: As of 12/31/2024, 5,140 AYA had prevalent T2D (57% female; 12% age 10-19; 88% age 20-30). Marked heterogeneity was observed (Figure 1): NHPI and Filipino AYA had the highest prevalence (13.2 and 12.5 per 1000, respectively), exceeding rates in Black, Hispanic, and Native American AYA (8.8-9.4 per 1000), groups traditionally considered at highest risk. T2D prevalence among Filipinos was elevated despite lower mean BMI. Conclusion: T2D burden varies across AsA and NHPI subgroups, sometimes exceeding that of other high-risk groups. Findings highlight the importance of disaggregating AsA and NHPI to identify high risk groups, and the need to refine screening guidelines and clinical risk assessment in these populations. Disclosure A. Kubo: None. J. Deardorff: None. S. Srinivasan: Research Support; Current; Abbott, Eli Lilly and Company. J.Y. Liu: None. J. Acker: None. S. Daredia: None. C.J. Huang: None. S. Negriff: None. A. Kanaya: None. A.J. Karter: Research Support; Current; Dexcom, Inc. Funding National Institutes of Health (R01DK139116)
Kubo et al. (Fri,) conducted a cohort in Type 2 diabetes (n=5,140). Native Hawaiian, Pacific Islander, and Filipino race/ethnicity vs. Black, Hispanic, and Native American race/ethnicity was evaluated on Standardized T2D prevalence per 1000. Native Hawaiian/Pacific Islander and Filipino adolescents and young adults had the highest T2D prevalence (13.2 and 12.5 per 1000), exceeding rates in Black, Hispanic, and Native American groups.