What question did this study set out to answer?

The aim is to understand the relationship between structure and function in RNA and other biological macromolecules.

June 18, 2026Open Access

RNA Structure and Function

SDShuchismita DuttaRutgers, The State University of New Jersey

Key Points

The aim is to understand the relationship between structure and function in RNA and other biological macromolecules.
Focus on key learning objectives regarding structure-function relationships in RNA and macromolecules.
Introduce concepts of covalent and noncovalent interactions in macromolecules.
Discuss primary, secondary, tertiary, and quaternary structures relevant to macromolecules.
Students will recognize repeating units in biological macromolecules.
Students will explain the influence of chemical and physical relationships on macromolecular structure.
Students will apply mechanistic reasoning to understand how enzymes and ribozymes catalyze reactions.

Abstract

ASBMB Learning Objectives (https://www.asbmb.org/education/core-concept-teaching-strategies/foundational-concepts/structure-function) 2. Structure is determined by several factors Students should be able to recognize the repeating units in biological macromolecules and be able to discuss the structural impacts of the covalent and noncovalent interactions involved (Introductory). Students should be able to discuss the chemical and physical relationships between composition and structure of macromolecules (Introductory). Students should be able to compare and contrast the primary, secondary, tertiary and quaternary structures of proteins and nucleic acids (Intermediate). 3. Structure and function are related Students should be able to use mechanistic reasoning to explain how an enzyme or ribozyme catalyzes a particular reaction (Introductory).

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