What type of study is this?

This is a Experimental Study study.

September 17, 2025

Distortion-Free Diffusion-Weighted Imaging of the Prostate Using TGSE-Based Golden-Angle PROPELLER Acquisition and Deep Learning Denoising

Key Points

DWI images produced with TGSE-PROPELLER are distortion-free, enabling clearer imaging around metal implants.
The acquisition scheme maintains high resolution comparable to clinical standards while reducing scan times.
A self-supervised deep learning model significantly enhances image quality by reducing noise in the acquired DWI images.
TGSE-PROPELLER's innovative approach demonstrates substantial improvements over conventional EPI-DWI methods.

Abstract

Motivation: Clinical single shot EPI-DWI suffers from low resolution and geometric distortion. Goal(s): To achieve distortion-free, high-resolution prostate DWI within the same or shorter scan time as the clinical routine. Approach: We developed a novel Turbo Gradient Spin Echo (TGSE) PROPELLER DWI acquisition scheme for prostate imaging, incorporating a self-supervised model for denoising. Blades corresponding to the same b-values are combined to produce b50 and b1000 images for ADC fitting. Results: DWI images generated with TGSE-PROPELLER-DWI are distortion-free, even in cases with metal implants or strong air-tissue induced B0 inhomogeneity. Higher-than-clinical resolution is achievable with the same scan time. Impact: TGSE-PROPELLER-DWI with a novel acquisition scheme provides distortion-free, high-resolution prostate DWI within the same scan time as the clinical protocol, with potential for further scan time reduction.

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Cite This Study

Chen et al. (Tue,) studied this question.

synapsesocial.com/papers/68d4597b31b076d99fa5cc30 https://doi.org/https://doi.org/10.58530/2025/0664

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