Figure S9 from Spatial Analysis of the Tumor Microenvironment in Diffuse Large B-cell Lymphoma Reveals Clinically Relevant Cell Interactions and Recurrent Cellular Neighborhoods

Key Points

• Significant interactions between B cells and PD-1+ T cells impact lymphoma behavior and cell organization.
• The study identifies recurrent cellular neighborhoods that are critical for understanding tumor dynamics in diffuse large B-cell lymphoma.
• Spatial analysis depicts how B cells are both attracted to and avoiding PD-1+ T cells, suggesting a complex relationship in the tumor microenvironment.
• Further exploration of these cell interactions could lead to improved therapeutic strategies in managing diffuse large B-cell lymphoma.