Key points are not available for this paper at this time.
In this work, an automated and scalable processing tool for Quantitative Susceptibility Mapping (QSM), QSMxT, is applied to a large dataset of 3D echo-planar imaging (3D-EPI) acquisitions of Multiple Sclerosis (MS) patients and volunteer controls. This is used to reconstruct QSMs for all subjects and generate a group space for the study. MS lesions are depicted and compared across multiple contrasts, including FLAIR, MP2RAGE, 3D-EPI magnitude and QSM. The group space is used to generate average QSM images for the MS and control groups along with a difference image to investigate iron accumulation and demyelination patterns.
Stewart et al. (Wed,) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: