Redox responsive cyclodextrin-based drug delivery systems: a special insight to glutathione responsive CD-nanosponges

Key Points

• To examine the characteristics and advantages of glutathione-responsive cyclodextrin nanosponges in drug delivery.
• Reviewed existing literature on cyclodextrin nanosponges
• Discussed structural properties and responsiveness
• Analyzed cross-linking density effects on drug delivery
• Identified key relationships between structure and drug release effectiveness
• Showed that cross-linking density influences responsiveness to glutathione
• Highlighted advantages of using nanosponges in targeted drug delivery