What question did this study set out to answer?

To evaluate advancements and ongoing challenges in cultured meat production for large-scale application.

February 2, 2026

Technological Advances and the Challenges for Large-Scale Cultured Meat Production

YXYunting XieNanjing Agricultural University SDShijie DingNanjing Institute of Technology YWYì WángBGI Group (China)

Key Points

To evaluate advancements and ongoing challenges in cultured meat production for large-scale application.
Review of recent technological advancements in cultured meat production.
Analysis of challenges regarding cost-effectiveness and safety.
Examination of regulatory frameworks and consumer acceptance.
Significant advances in seed cell acquisition and serum-free culture media.
Breakthroughs in bioreactor scale-up and 3D tissue formation.
Ongoing challenges in achieving cost-effective production and consumer acceptance.

Abstract

Cultured meat, produced through in vitro cultivation of animal cells, represents a promising solution to the environmental, ethical, and resource-intensive challenges of conventional livestock production. Significant technological advances have been achieved in seed cell acquisition, serum-free culture media development, bioreactor scale-up, 3D tissue formation, and sensory enhancement. Nevertheless, substantial hurdles persist in achieving cost-effective large-scale production, ensuring product safety and quality, establishing robust regulatory frameworks, and securing widespread consumer acceptance. This review examines recent progress throughout the cultured meat production chain, critically analyzes unresolved challenges, and outlines essential research priorities for realizing its industrial potential.

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