Phenotypic age acceleration and early-onset lung cancer: a case–control and prognostic cohort study involving multiple clinical centres with validation in the UK Biobank | Synapse
Phenotypic age acceleration and early-onset lung cancer: a case–control and prognostic cohort study involving multiple clinical centres with validation in the UK Biobank
This research investigates the relationship between phenotypic age acceleration and the incidence of early-onset lung cancer.
Conducted a case-control study involving multiple clinical centres
Involved a prognostic cohort analysis
Utilized clinical data for validation in the UK Biobank
Identified significant correlation between phenotypic age acceleration and early lung cancer onset
Demonstrated that faster aging traits could serve as potential biomarkers for lung cancer risk
Abstract
National Natural Science Foundation of China (no. 82303969); Beijing Xisike Clinical Oncology Research Foundation (no. Y-2024AZ EGFRMS-0079); Beijing Natural Science Foundation (no. 7222144).