Molecular Anatomy of GLP‐1 Signaling in the Human Nodose Ganglion

Key Points

• This study aims to define the expression of GLP-1 receptors in human and mouse nodose ganglion tissue.
• Comparative analysis of GLP-1 receptor expression in mouse and human nodose ganglion.
• Utilization of immunohistochemical techniques to visualize receptor presence.
• Characterization of peripheral sensory targets associated with GLP-1 signaling.
• GLP-1 receptor expression is confirmed in the nodose ganglion of both species.
• The findings suggest a conserved role for GLP-1 signaling in peripheral sensory functions.
• Differences in expression levels between mouse and human nodose ganglion indicate species-specific adaptations.