Appropriate ICD therapy was linked to a lower Body Mass Index (BMI), higher left ventricular end-systolic diameter (LVESD), and elevated albumin levels in patients with Heart Failure and Reduced Ejection Fraction.
Cohort (n=288)
No
Do nutritional indices (NPS, PNI, CONUT) predict appropriate ICD therapy in patients with HFrEF receiving primary prevention ICDs?
While nutritional indices like NPS, PNI, and CONUT show univariate associations with appropriate ICD therapy in HFrEF patients, only lower BMI, higher LVESD, and elevated albumin are independent predictors in multivariable analysis.
Effect estimate: OR: 3.303 (95% CI 1.846-5.910)
Absolute Event Rate: 94% vs 194%
p-value: p=<0.001
Aims: To evaluate the predictive value of the Naples prognostic score (NPS) and other nutritional indices for appropriate implantable cardioverter-defibrillator (ICD) therapy in primary prevention patients with heart failure with reduced ejection fraction (HFrEF).Methods: This retrospective cohort study included 288 adult patients with HFrEF who underwent primary prevention ICD implantation and followed for at least six months. Data were retrospectively collected from electronic medical records. The NPS, PNI, and CONUT scores were calculated from baseline laboratory values obtained at the time of ICD implantation. The primary endpoint was the predictive performance of NPS for appropriate ICD therapy.Results: Patients with appropriate therapy (n=194) were younger (p=0.002), had lower BMI (p
Könte et al. (Tue,) conducted a cohort in Heart Failure with Reduced Ejection Fraction (n=288). Implantable cardioverter-defibrillator (ICD) therapy vs. No appropriate ICD therapy was evaluated on Predictive value of the Naples Prognostic Score for appropriate ICD therapy (OR: 3.303, 95% CI 1.846-5.910, p=<0.001). Appropriate ICD therapy was linked to a lower Body Mass Index (BMI), higher left ventricular end-systolic diameter (LVESD), and elevated albumin levels in patients with Heart Failure and Reduced Ejection Fraction.