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April 1, 2026

The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID

Key Points

The aim is to assess the effectiveness of fluvoxamine and metformin in reducing fatigue associated with long COVID.
Assessing patient symptoms pre- and post-treatment with fluvoxamine and metformin
Utilizing standardized fatigue measurement scales
Comparing results among participants with long COVID
Reduction in fatigue levels among patients using fluvoxamine
Improvement in overall wellbeing noted with metformin usage
Combination of both medications shows potential for enhanced effects

Abstract

Postacute sequelae of SARS-CoV-2, or long COVID, presents a major therapeutic challenge, with fatigue being a prevalent and debilitating symptom.

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Cite This Study

Reis et al. (Mon,) studied this question.

synapsesocial.com/papers/69cd79e15652765b073a6bf4 https://doi.org/https://doi.org/10.7326/annals-25-03959

The Effect of Fluvoxamine and Metformin for Fatigue in Patients With Long COVID | Synapse