A systematic review of human status epilepticus in organophosphate poisoning: A real‐world Stage 1 Plus model?

Key Points

• To explore the relationship between organophosphate poisoning and status epilepticus in humans, particularly emphasizing the variability and severity of seizures.
• Conducted a systematic review of available literature on organophosphate poisoning and seizures.
• Analyzed clinical features of status epilepticus in affected individuals.
• Examined the effectiveness of early benzodiazepine treatment in managing seizures.
• Found that organophosphate poisoning often leads to convulsive status epilepticus.
• Ongoing seizures were common even after initial benzodiazepine therapy.
• Suggested that early use of polytherapy may be necessary to better manage seizure episodes.