A systematic review examines organophosphate poisoning's effects on seizures, suggesting need for early treatments.
OP poisoning is a polymorphic entity including several cholinergic features and a broad SE spectrum, mainly convulsive SE. Ongoing seizures after early BDZ therapy suggest a possible direction toward a Stage 1 Plus phenotype, mirroring experimental evidence from preclinical animal models of OP-induced SE, possibly requiring early polytherapy.
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Magro et al. (2026) studied this question.
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