Microbial-enzymatic co-fermentation enhanced the beneficial effects of highland barley bran on preventing metabolic disorders and gut microbiota dysbiosis induced by high-fat diet in obese mice | Synapse
April 8, 2026Food & Function1 citations
Microbial-enzymatic co-fermentation enhanced the beneficial effects of highland barley bran on preventing metabolic disorders and gut microbiota dysbiosis induced by high-fat diet in obese mice
The central aim is to assess how microbial-enzymatic co-fermentation of highland barley bran influences gut microbiota and metabolic health in obese mice.
Administered highland barley bran and fermented products to obese mice
Monitored metabolic markers and gut microbiota composition
Performed comparative analysis against control groups
Microbial-enzymatic co-fermentation significantly improved bioavailability of phenolic compounds
Reduced incidence of metabolic disorders in treated mice
Enhanced diversity of gut microbiota was observed with treatment
Abstract
Highland barley bran (HBB) is rich in phenolic compounds, but they predominantly exist in bound forms, which severely affect their bioavailability and efficacy. This study aimed to investigate the effect...