What question did this study set out to answer?

To investigate the effectiveness of nickel-catalyzed Sonogashira reactions without traditional co-catalysts and heating.

April 15, 2026Open Access

Electromagnetic Milling-Promoted Steel Rods-enabled Sonogashira Coupling Reactions of Aryl halides and Terminal alkynes

Key Points

To investigate the effectiveness of nickel-catalyzed Sonogashira reactions without traditional co-catalysts and heating.
Conducted Sonogashira reactions using nickel as the main catalyst.
Utilized electromagnetic milling to promote reactions.
Examined the coupling between aryl halides and terminal alkynes.
Successfully achieved C(sp²)–C(sp) bond formation without copper co-catalysts.
Reduced need for solvents and inert atmospheres in the reaction process.

Abstract

Nickel-catalyzed Sonogashira reactions between aryl halides and terminal alkynes have become a powerful method for constructing C(sp²)–C(sp) bonds. Conventional approaches typically required copper co-catalysts, solvents, inert atmospheres, and external heating....

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Authors

Xinyao Liu

Shandong University of Technology

Yanyan Chen

Shandong University of Technology

Qiuhong Ma

Binzhou University

Journals

RSC Mechanochemistry

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Building similarity graph...

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Electromagnetic Milling-Promoted Steel Rods-enabled Sonogashira Coupling Reactions of Aryl halides and Terminal alkynes

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

References and Citations

Citation Network

Connected Papers

Discussion

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