What question did this study set out to answer?

To investigate the effectiveness of nickel-catalyzed Sonogashira reactions without traditional co-catalysts and heating.

April 15, 2026Open Access

Electromagnetic Milling-Promoted Steel Rods-enabled Sonogashira Coupling Reactions of Aryl halides and Terminal alkynes

Key Points

To investigate the effectiveness of nickel-catalyzed Sonogashira reactions without traditional co-catalysts and heating.
Conducted Sonogashira reactions using nickel as the main catalyst.
Utilized electromagnetic milling to promote reactions.
Examined the coupling between aryl halides and terminal alkynes.
Successfully achieved C(sp²)–C(sp) bond formation without copper co-catalysts.
Reduced need for solvents and inert atmospheres in the reaction process.

Abstract

Nickel-catalyzed Sonogashira reactions between aryl halides and terminal alkynes have become a powerful method for constructing C(sp²)–C(sp) bonds. Conventional approaches typically required copper co-catalysts, solvents, inert atmospheres, and external heating....

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Cite this study

Liu et al. (Thu,) studied this question.

synapsesocial.com/papers/69df2b65e4eeef8a2a6b05f0 — DOI: https://doi.org/10.1039/d6mr00022c

Authors

Xinyao Liu

Shandong University of Technology

Yanyan Chen

Shandong University of Technology

Qiuhong Ma

Binzhou University

Journals

RSC Mechanochemistry

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References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Electromagnetic Milling-Promoted Steel Rods-enabled Sonogashira Coupling Reactions of Aryl halides and Terminal alkynes

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

References and Citations

Citation Network

Connected Papers

Discussion