November 14, 2006
Prevention of High-Dose Chemotherapy–Induced Cardiotoxicity in High-Risk Patients by Angiotensin-Converting Enzyme Inhibition
Structured PICO
Does early treatment with enalapril prevent the development of late cardiotoxicity in high-risk patients treated with high-dose chemotherapy?
P
Population
High-risk patients treated with high-dose chemotherapy (HDC), defined by an increased troponin I value
I
Intervention
Early treatment with enalapril
O
Outcome
Development of late cardiotoxicity
Early initiation of enalapril in patients receiving high-dose chemotherapy who develop elevated troponin I may prevent subsequent cardiotoxicity.
Abstract
In high-risk, HDC-treated patients, defined by an increased troponin I value, early treatment with enalapril seems to prevent the development of late cardiotoxicity.
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Authors
Daniela Cardinale
University of Modena and Reggio Emilia
A
Alessandro Colombo
NTT (Italy)
M
Maria Teresa Sandri
Cardio-Oncology
Journals
Circulation
Actions
Institutions
I.R.C.C.S. Oasi Maria SS
References and Citations
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