Palladium-catalyzed domino sequence of ortho-X-allenyl tethered aryl isocyanides: access to fused benzazole frameworks

Key Points

• This research aims to explore a new palladium-catalyzed domino sequence using ortho-X-allenyl tethered aryl isocyanides to synthesize fused benzazole frameworks.
• Developed a palladium-catalyzed domino sequence using ortho-X-allenyl tethered aryl isocyanides as substrates.
• Synthesized a variety of fused benzazole frameworks through this novel reaction.
• Characterized products using standard analytical techniques.
• Successfully synthesized multiple fused benzazole structures with high efficiency.
• Reaction conditions optimized to enhance product yield and selectivity.
• Significant reduction in synthesis time compared to traditional methods.