What question did this study set out to answer?

This study aims to investigate the efficacy of hybrid therapy combining microembolization and coiling for treating primary cardiac angiosarcoma.

May 9, 2026Kardiologia Polska0 citationsOpen Access

Primary cardiac angiosarcoma — hybrid therapy using coronary microembolization with coiling

EPEdward PietrzykFoundation of Cardiac Surgery Development APAnna PolewczykElectrophysiology MSMichał SpałekJan Kochanowski University

Key Points

This study aims to investigate the efficacy of hybrid therapy combining microembolization and coiling for treating primary cardiac angiosarcoma.
Utilized a hybrid therapy approach involving coronary microembolization and coiling.

Structured PICO

Population

A 54-year-old man, former smoker with hyperlipidaemia, presenting with a large primary cardiac angiosarcoma (grade G3) in the right atrium with invasion of the inferior vena cava.

Intervention

Hybrid therapy comprising partial surgical debulking, chemotherapy (doxorubicin and dacarbazine), and superselective transarterial embolization of the coronary artery feeding the tumor using HydroPearl microspheres (200 µm ± 75 µm) and an Azur circumflex coil.

Outcome

Tumor size reduction and clinical improvementsurrogate

Superselective transarterial embolization of the coronary artery feeding a primary cardiac angiosarcoma can reduce tumor mass and provide clinical improvement as part of a hybrid therapeutic approach.

Abstract

Primary cardiac sarcomas are extremely rare malignant tumors, accounting for 0.001% to 0.3%

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