January 1, 2022Open Access

M2 microglia-derived extracellular vesicles promote white matter repair and functional recovery via miR-23a-5p after cerebral ischemia in mice

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Abstract

Our results demonstrated that M2 microglia could communicate to OPCs through M2-EVs and promote white matter repair via miR-23a-5p possibly by directly targeting Olig3 after ischemic stroke, suggesting M2-EVs is a novel and promising therapeutic strategy for white matter repair in stroke and demyelinating disease.

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Li et al. (Sat,) studied this question.

synapsesocial.com/papers/6a03e5c010f10246154d240d https://doi.org/https://doi.org/10.7150/thno.68895

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